InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Slc6a14

Summary

InnateDB Protein

IDBP-136058.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Slc6a14

Protein Name

solute carrier family 6 (neurotransmitter transporter), member 14

Synonyms

1110007A17Rik; 9030613J17Rik; ATB0plus; CATB0plus;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000033414

InnateDB Gene

IDBG-136056 (Slc6a14)

Protein Structure

UniProt Annotation

Function

Mediates the uptake of a broad range of neutral and cationic amino acids (with the exception of proline) in a Na(+)/Cl(-)-dependent manner. {ECO:0000269PubMed:11306607, ECO:0000269PubMed:11447016}.

Subcellular Localization

Membrane; Multi-pass membrane protein.

Disease Associations

Tissue Specificity

Expressed in the distal region of the intestinal tract: cecum and colon. {ECO:0000269PubMed:11306607, ECO:0000269PubMed:11447016}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005275	amine transmembrane transporter activity
GO:0005328	neurotransmitter:sodium symporter activity

Biological Process

GO:0006836	neurotransmitter transport
GO:0006865	amino acid transport
GO:0009636	response to toxic substance
GO:0015837	amine transport
GO:0055085	transmembrane transport

Cellular Component

GO:0005887	integral component of plasma membrane
GO:0016021	integral component of membrane
GO:0031526	brush border membrane
GO:0070062	extracellular vesicular exosome