InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Arhgef10

Summary

InnateDB Protein

IDBP-136430.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Arhgef10

Protein Name

Rho guanine nucleotide exchange factor (GEF) 10

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000081225

InnateDB Gene

IDBG-136428 (Arhgef10)

Protein Structure

UniProt Annotation

Function

May play a role in developmental myelination of peripheral nerves. {ECO:0000269PubMed:14508709}.

Subcellular Localization

Disease Associations

Tissue Specificity

Ubiquitously expressed. {ECO:0000269PubMed:14508709}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.

Predicted by orthology
Total	2 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005089	Rho guanyl-nucleotide exchange factor activity
GO:0005515	protein binding
GO:0019894	kinesin binding

Biological Process

GO:0022011	myelination in peripheral nervous system
GO:0032319	regulation of Rho GTPase activity
GO:0033126	positive regulation of GTP catabolic process
GO:0035023	regulation of Rho protein signal transduction
GO:0051298	centrosome duplication
GO:0051496	positive regulation of stress fiber assembly
GO:0090307	spindle assembly involved in mitosis