Version 5.4
Mus musculus Protein: Ube2r2
Summary
InnateDB Protein IDBP-137401.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ube2r2
Protein Name ubiquitin-conjugating enzyme E2R 2
Synonyms 1200003M11Rik; Cdc34b; Ubc3b;
Species Mus musculus
Ensembl Protein ENSMUSP00000038813
InnateDB Gene IDBG-137399 (Ube2r2)
Protein Structure
UniProt Annotation
Function Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes monoubiquitination and 'Lys-48'-linked polyubiquitination. May be involved in degradation of katenin (By similarity). {ECO:0000250}.
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 10 interaction(s) predicted by orthology.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 10 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004842 ubiquitin-protein transferase activity
GO:0005524 ATP binding
GO:0016881 acid-amino acid ligase activity
Biological Process
GO:0006513 protein monoubiquitination
GO:0070936 protein K48-linked ubiquitination
Cellular Component
GO:0005575 cellular_component
Protein Structure and Domains
PDB ID MGI:1914865
InterPro IPR000608 Ubiquitin-conjugating enzyme, E2
IPR016135 Ubiquitin-conjugating enzyme/RWD-like
PFAM PF00179
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q6ZWZ2
PhosphoSite PhosphoSite-Q6ZWZ2
TrEMBL
UniProt Splice Variant
Entrez Gene 67615
UniGene Mm.389540
RefSeq NP_080551
MGI ID
MGI Symbol Ube2r2
OMIM
CCDS CCDS18057
HPRD
IMGT
EMBL AJ240086 AK003550 AK007517 AK075703 AK075714 AL807823 AL954379 BC011112
GenPept AAH11112 BAB22850 BAB25085 BAC35899 BAC35904 CAC80335 CAM20979 CAM27658

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca