InnateDB Protein
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IDBP-13786.7
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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TRNT1
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Protein Name
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tRNA nucleotidyl transferase, CCA-adding, 1
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Synonyms
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000280591
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InnateDB Gene
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IDBG-13784 (TRNT1)
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Protein Structure
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Function |
Isoform 1: Adds and repairs the conserved 3'-CCA sequence necessary for the attachment of amino acids to the 3' terminus of tRNA molecules, using CTP and ATP as substrates.Isoform 2: Adds 2 C residues (CC-) to the 3' terminus of tRNA molecules instead of a complete CCA end as isoform 1 does (in vitro).
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Subcellular Localization |
Mitochondrion {ECO:0000269PubMed:11256614}.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 17 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
17
[view]
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Protein-Protein |
17
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR002646
Poly A polymerase, head domain
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PFAM |
PF01743
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q96Q11
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PhosphoSite |
PhosphoSite-Q96Q11
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TrEMBL |
C9JRS7
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UniProt Splice Variant |
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Entrez Gene |
51095
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UniGene |
Hs.732860
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RefSeq |
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HUGO |
HGNC:17341
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OMIM |
612907
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CCDS |
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HPRD |
18227
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IMGT |
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EMBL |
AB063105
AC024060
AF151805
AK290411
AL834397
BC005184
BC012537
CH471055
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GenPept |
AAD34042
AAH05184
AAH12537
BAB70662
BAF83100
CAD39059
EAW63886
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