InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Tgtp1

Summary

InnateDB Protein

IDBP-137871.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Tgtp1

Protein Name

T-cell specific GTPase 1

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000069914

InnateDB Gene

IDBG-262889 (Tgtp1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.

Experimentally validated
Total	4 [view]
Protein-Protein	3 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003924	GTPase activity
GO:0005525	GTP binding
GO:0016817	hydrolase activity, acting on acid anhydrides

Biological Process

GO:0006184	GTP catabolic process
GO:0006955	immune response
GO:0008152	metabolic process
GO:0009615	response to virus
GO:0045087	innate immune response (InnateDB)

Cellular Component

GO:0005622	intracellular
GO:0016020	membrane

Protein Structure and Domains

PDB ID

MGI:98734

InterPro

IPR007743 Interferon-inducible GTPase
IPR027417 P-loop containing nucleoside triphosphate hydrolase

PFAM

PF05049

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-NP_035709

TrEMBL

Q62293

UniProt Splice Variant

Entrez Gene

21822

UniGene

Mm.15793

RefSeq

NP_035709

MGI ID

MGI Symbol

Tgtp1

OMIM

CCDS

CCDS24593

HPRD

IMGT

EMBL

AK088858 AK163978 AK172473 AL627237 AL645688 BC085259 CH466575 FR734025 FR734026 L38444

GenPept

AAA64914 AAH85259 BAC40617 BAE37565 BAE43026 CBY65988 CBY65989 EDL33781