InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Nudt2

Summary

InnateDB Protein

IDBP-137880.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Nudt2

Protein Name

nudix (nucleoside diphosphate linked moiety X)-type motif 2

Synonyms

2310051L06Rik; AA939917; APAH1;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000030154

InnateDB Gene

IDBG-137878 (Nudt2)

Protein Structure

UniProt Annotation

Function

Asymmetrically hydrolyzes Ap4A to yield AMP and ATP. Plays a major role in maintaining homeostasis (By similarity). {ECO:0000250}.

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.

Predicted by orthology
Total	4 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004081	bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) activity
GO:0005525	GTP binding
GO:0016787	hydrolase activity

Biological Process

GO:0006915	apoptotic process
GO:0008152	metabolic process

Cellular Component

GO:0005739

mitochondrion

Protein Structure and Domains

PDB ID

MGI:1913651

InterPro

IPR000086 NUDIX hydrolase domain
IPR003565 Bis(5\'-nucleosyl)-tetraphosphatase
IPR015797 NUDIX hydrolase domain-like

PFAM

PF00293

PRINTS

PR01405

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

P56380

PhosphoSite

PhosphoSite-P56380

TrEMBL

UniProt Splice Variant

Entrez Gene

66401

UniGene

Mm.28574

RefSeq

NP_079815

MGI ID

MGI Symbol

Nudt2

OMIM

CCDS

CCDS18061

HPRD

IMGT

EMBL

AK009933 AK018771 BC025153

GenPept

AAH25153 BAB26592 BAB31399