InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Dlg5

Summary

InnateDB Protein

IDBP-138096.5

Last Modified

2012-02-14 [Report errors or provide feedback]

Gene Symbol

Dlg5

Protein Name

discs, large homolog 5 (Drosophila)

Synonyms

4933429D20Rik; mKIAA0583; T25557;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000087879

InnateDB Gene

IDBG-138094 (Dlg5)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.

Predicted by orthology
Total	8 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0008013	beta-catenin binding
GO:0008092	cytoskeletal protein binding

Biological Process

GO:0006461	protein complex assembly
GO:0030859	polarized epithelial cell differentiation
GO:0030901	midbrain development
GO:0042981	regulation of apoptotic process
GO:0045176	apical protein localization
GO:0045186	zonula adherens assembly
GO:0045197	establishment or maintenance of epithelial cell apical/basal polarity
GO:0060441	epithelial tube branching involved in lung morphogenesis
GO:0071896	protein localization to adherens junction
GO:0072205	metanephric collecting duct development

Cellular Component

GO:0005622	intracellular
GO:0005913	cell-cell adherens junction

Protein Structure and Domains

PDB ID

MGI:1918478

InterPro

IPR001315 CARD domain
IPR001452 SH3 domain
IPR001478 PDZ domain
IPR006907 Domain of unknown function DUF622
IPR008144 Guanylate kinase-like
IPR008145 Guanylate kinase/L-type calcium channel beta subunit
IPR011029 Death-like domain
IPR027417 P-loop containing nucleoside triphosphate hydrolase

PFAM