InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Stip1

Summary

InnateDB Protein

IDBP-138161.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Stip1

Protein Name

stress-induced phosphoprotein 1

Synonyms

Hop; p60; Sti1;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000025918

InnateDB Gene

IDBG-138159 (Stip1)

Protein Structure

UniProt Annotation

Function

Mediates the association of the molecular chaperones HSC70 and HSP90 (HSPCA and HSPCB).

Subcellular Localization

Cytoplasm {ECO:0000269PubMed:8999875}. Nucleus {ECO:0000269PubMed:8999875}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
They are also associated with 56 interaction(s) predicted by orthology.

Experimentally validated
Total	6 [view]
Protein-Protein	6 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	56 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0044822	poly(A) RNA binding

Biological Process

Cellular Component

GO:0005634	nucleus
GO:0005829	cytosol

Protein Structure and Domains

PDB ID

MGI:109130

InterPro

IPR001440 Tetratricopeptide TPR1
IPR006636 Heat shock chaperonin-binding
IPR013026 Tetratricopeptide repeat-containing domain
IPR013105 Tetratricopeptide TPR2
IPR019734 Tetratricopeptide repeat

PFAM

PF00515
PF07719
PF13174
PF13176
PF13181

PRINTS

PIRSF

SMART

SM00727
SM00028

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q60864