Version 5.4
Mus musculus Protein: Crkl
Summary
InnateDB Protein IDBP-138915.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Crkl
Protein Name v-crk sarcoma virus CT10 oncogene homolog (avian)-like
Synonyms 1110025F07Rik; AA589403; AI325100; Crkol;
Species Mus musculus
Ensembl Protein ENSMUSP00000006293
InnateDB Gene IDBG-138913 (Crkl)
Protein Structure
UniProt Annotation
Function May mediate the transduction of intracellular signals.
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 24 experimentally validated interaction(s) in this database.
They are also associated with 76 interaction(s) predicted by orthology.
Experimentally validated
Total 24 [view]
Protein-Protein 24 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 76 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0044822 poly(A) RNA binding
Biological Process
GO:0001568 blood vessel development
GO:0007389 pattern specification process
GO:0007507 heart development
GO:0009887 organ morphogenesis
GO:0009952 anterior/posterior pattern specification
GO:0048538 thymus development
GO:0060017 parathyroid gland development
Cellular Component
GO:0005737 cytoplasm
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID MGI:104686
InterPro IPR000980 SH2 domain
IPR001452 SH3 domain
IPR011511 Variant SH3 domain
PFAM PF00017
PF14633
PF00018
PF14604
PF07653
PRINTS PR00401
PR00452
PIRSF
SMART SM00252
SM00326
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P47941
PhosphoSite PhosphoSite-P47941
TrEMBL A2RS58
UniProt Splice Variant
Entrez Gene 12929
UniGene Mm.407247
RefSeq NP_031790
MGI ID
MGI Symbol Crkl
OMIM
CCDS CCDS28002
HPRD
IMGT
EMBL AK048641 AK052315 AK163981 BC131984 BC131986 CH466521 X90648
GenPept AAI31985 AAI31987 BAC33406 BAC34933 BAE37567 CAA62220 EDK97459

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca