Version 5.4
Mus musculus Protein: Nebl
Summary
InnateDB Protein IDBP-139019.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Nebl
Protein Name nebulette
Synonyms 1200007O21Rik; A630080F05Rik; BB140644; D830029A09Rik; Lnebl;
Species Mus musculus
Ensembl Protein ENSMUSP00000028080
InnateDB Gene IDBG-139017 (Nebl)
Protein Structure
UniProt Annotation
Function Binds to actin and plays an important role in the assembly of the Z-disk. Isoform 2 might play a role in the assembly of focal adhesion (By similarity). {ECO:0000250}.
Subcellular Localization Isoform 2: Cytoplasm {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 5 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003779 actin binding
GO:0005515 protein binding
GO:0008270 zinc ion binding
Biological Process
Cellular Component
GO:0005737 cytoplasm
Protein Structure and Domains
PDB ID MGI:1921353
InterPro IPR000900 Nebulin repeat
IPR001452 SH3 domain
IPR001781 Zinc finger, LIM-type
IPR011511 Variant SH3 domain
PFAM PF00880
PF00018
PF14604
PF00412
PF07653
PRINTS PR00452
PIRSF
SMART SM00227
SM00326
SM00132
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9DC07
PhosphoSite PhosphoSite-Q9DC07
TrEMBL
UniProt Splice Variant
Entrez Gene 74103
UniGene Mm.462602
RefSeq NP_083033
MGI ID
MGI Symbol Nebl
OMIM
CCDS CCDS15706
HPRD
IMGT
EMBL AK004645 AL772218 AL845498 AL935297 AL954131 BC025863 CH466542
GenPept AAH25863 BAB23436 CAM14501 CAM17882 CAM21080 EDL08088

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca