InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Gpld1

Summary

InnateDB Protein

IDBP-139372.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Gpld1

Protein Name

glycosylphosphatidylinositol specific phospholipase D1

Synonyms

6330541J12Rik; AW546131;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000021773

InnateDB Gene

IDBG-139370 (Gpld1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.

Predicted by orthology
Total	2 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004621	glycosylphosphatidylinositol phospholipase D activity
GO:0004630	phospholipase D activity
GO:0005515	protein binding

Biological Process

GO:0002042	cell migration involved in sprouting angiogenesis
GO:0002430	complement receptor mediated signaling pathway
GO:0006507	GPI anchor release
GO:0008285	negative regulation of cell proliferation
GO:0008286	insulin receptor signaling pathway
GO:0009749	response to glucose
GO:0010595	positive regulation of endothelial cell migration
GO:0032869	cellular response to insulin stimulus
GO:0035690	cellular response to drug
GO:0043065	positive regulation of apoptotic process
GO:0045919	positive regulation of cytolysis
GO:0051044	positive regulation of membrane protein ectodomain proteolysis
GO:0071277	cellular response to calcium ion
GO:0071397	cellular response to cholesterol
GO:0071401	cellular response to triglyceride
GO:0071467	cellular response to pH
GO:1900076	regulation of cellular response to insulin stimulus

Cellular Component

GO:0005578	proteinaceous extracellular matrix
GO:0005615	extracellular space
GO:0005622	intracellular
GO:0005765	lysosomal membrane
GO:0043231	intracellular membrane-bounded organelle