InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Tas2r138

Summary

InnateDB Protein

IDBP-139421.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Tas2r138

Protein Name

taste receptor, type 2, member 138

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000075876

InnateDB Gene

IDBG-139419 (Tas2r138)

Protein Structure

UniProt Annotation

Function

Putative taste receptor which may play a role in the perception of bitterness. {ECO:0000303PubMed:12734386}.

Subcellular Localization

Membrane; Multi-pass membrane protein.

Disease Associations

Tissue Specificity

Low levels in tongue, stomach and duodenum. {ECO:0000269PubMed:15886333}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.

Experimentally validated
Total	1 [view]
Protein-Protein	0
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004930	G-protein coupled receptor activity
GO:0008527	taste receptor activity
GO:0033038	bitter taste receptor activity

Biological Process

GO:0001580	detection of chemical stimulus involved in sensory perception of bitter taste
GO:0007186	G-protein coupled receptor signaling pathway
GO:0050909	sensory perception of taste

Cellular Component

GO:0016021

integral component of membrane

Protein Structure and Domains

PDB ID

MGI:2681306

InterPro

IPR007960 Mammalian taste receptor

PFAM

PF05296

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q7TQA6

PhosphoSite

PhosphoSite-

TrEMBL

UniProt Splice Variant

Entrez Gene

387513

UniGene

Mm.377920

RefSeq

NP_001001451

MGI ID

MGI Symbol

Tas2r138

OMIM

CCDS

CCDS20038

HPRD

IMGT

EMBL

AC153378 AF532789 AY916509 BC128016 BK001093

GenPept

AAI28017 AAP40339 AAX99132 DAA01232