InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Fancg

Summary

InnateDB Protein

IDBP-139856.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Fancg

Protein Name

Fanconi anemia, complementation group G

Synonyms

AU041407; Xrcc9;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000030165

InnateDB Gene

IDBG-139854 (Fancg)

Protein Structure

UniProt Annotation

Function

DNA repair protein that may operate in a postreplication repair or a cell cycle checkpoint function. May be implicated in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability. Candidate tumor suppressor gene (By similarity). {ECO:0000250}.

Subcellular Localization

Nucleus {ECO:0000269PubMed:11918676}.

Disease Associations

Tissue Specificity

Highest expression levels in spleen, thymus and testis. {ECO:0000269PubMed:11918676}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 36 interaction(s) predicted by orthology.

Experimentally validated
Total	1 [view]
Protein-Protein	1 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	36 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding

Biological Process

GO:0001541	ovarian follicle development
GO:0006281	DNA repair
GO:0006974	cellular response to DNA damage stimulus
GO:0007005	mitochondrion organization
GO:0007286	spermatid development
GO:0009314	response to radiation