InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Prl

Summary

InnateDB Protein

IDBP-139891.5

Last Modified

2012-02-14 [Report errors or provide feedback]

Gene Symbol

Prl

Protein Name

prolactin

Synonyms

AV290867; Prl1a1;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000018061

InnateDB Gene

IDBG-139889 (Prl)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.

Experimentally validated
Total	1 [view]
Protein-Protein	1 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005179	hormone activity

Biological Process

GO:0007262	STAT protein import into nucleus
GO:0008284	positive regulation of cell proliferation
GO:0030879	mammary gland development
GO:0045087	innate immune response (InnateDB)
GO:0046425	regulation of JAK-STAT cascade
GO:0046427	positive regulation of JAK-STAT cascade

Cellular Component

GO:0005576	extracellular region
GO:0030141	secretory granule

Protein Structure and Domains

PDB ID

MGI:97762

InterPro

IPR001400 Somatotropin hormone
IPR009079 Four-helical cytokine-like, core

PFAM

PF00103

PRINTS

PR00836

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

Q9CPQ0

UniProt Splice Variant

Entrez Gene

19109

UniGene

RefSeq

MGI ID

MGI Symbol

Prl

OMIM

CCDS

HPRD

IMGT

EMBL

AK017520 AK017584 AK133645 AK161553 AK161594 AL591843 CH466561

GenPept

BAB30786 BAB30821 BAE21763 BAE36459 BAE36481 EDL32453