Version 5.4
Mus musculus Protein: Dgcr14
Summary
InnateDB Protein IDBP-140767.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Dgcr14
Protein Name DiGeorge syndrome critical region gene 14
Synonyms AI462402; D16H22S1269E; Dgcr1; Dgsi; ES2; Es2el;
Species Mus musculus
Ensembl Protein ENSMUSP00000003621
InnateDB Gene IDBG-140765 (Dgcr14)
Protein Structure
UniProt Annotation
Function May be involved in pre-mRNA splicing. {ECO:0000250}.
Subcellular Localization Nucleus.
Disease Associations
Tissue Specificity In the adult, widely expressed with highest expression in the testis and brain. Also widely expressed in the embryo with highest levels in the anterior pons.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 12 interaction(s) predicted by orthology.
Predicted by orthology
Total 12 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0005515 protein binding
Biological Process
GO:0006397 mRNA processing
GO:0007399 nervous system development
GO:0008380 RNA splicing
Cellular Component
GO:0005634 nucleus
GO:0071013 catalytic step 2 spliceosome
Protein Structure and Domains
PDB ID MGI:107854
InterPro IPR019148 Nuclear protein DGCR14
PFAM PF09751
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt O70279
PhosphoSite PhosphoSite-O70279
TrEMBL Q3UFM6
UniProt Splice Variant
Entrez Gene 27886
UniGene Mm.256480
RefSeq NP_071853
MGI ID
MGI Symbol Dgcr14
OMIM
CCDS CCDS28013
HPRD
IMGT
EMBL AC004412 AC078895 AF037256 AK088520 AK148404 BC013711 CH466521
GenPept AAC40077 AAH13711 BAC40400 BAE28534 EDK97492

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca