Mus musculus Protein: Rtn4r
Summary
InnateDB Protein IDBP-141122.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Rtn4r
Protein Name reticulon 4 receptor
Synonyms NgR; NgR1; NOGOR;
Species Mus musculus
Ensembl Protein ENSMUSP00000062924
InnateDB Gene IDBG-141120 (Rtn4r)
Protein Structure
UniProt Annotation
Function Receptor for RTN4, OMG and MAG. Mediates axonal growth inhibition and may play a role in regulating axonal regeneration and plasticity in the adult central nervous system (By similarity). Acts in conjunction with RTN4 and LIGO1 in regulating neuronal precursor cell motility during cortical development. {ECO:0000250, ECO:0000269PubMed:11201742, ECO:0000269PubMed:20093372}.
Subcellular Localization Cell membrane {ECO:0000250}; Lipid-anchor, GPI-anchor {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 5 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0007409 axonogenesis
Cellular Component
GO:0005783 endoplasmic reticulum
GO:0005886 plasma membrane
GO:0009986 cell surface
GO:0031225 anchored component of membrane
Protein Structure and Domains
PDB ID MGI:2136886
InterPro IPR001611 Leucine-rich repeat
IPR003591 Leucine-rich repeat, typical subtype
PFAM PF00560
PF13504
PF13855
PRINTS
PIRSF
SMART SM00369
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q99PI8
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 65079
UniGene Mm.40149
RefSeq NP_075358
MGI ID
MGI Symbol Rtn4r
OMIM
CCDS CCDS37279
HPRD
IMGT
EMBL AF283462 BC052317 BC058381
GenPept AAG53611 AAH52317 AAH58381