InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Pax9

Summary

InnateDB Protein

IDBP-141256.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Pax9

Protein Name

paired box gene 9

Synonyms

Pax-9;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000001538

InnateDB Gene

IDBG-141254 (Pax9)

Protein Structure

UniProt Annotation

Function

Transcription factor required for normal development of thymus, parathyroid glands, ultimobranchial bodies, teeth, skeletal elements of skull and larynx as well as distal limbs. {ECO:0000269PubMed:9732271}.

Subcellular Localization

Nucleus.

Disease Associations

Tissue Specificity

In the embryo, expressed in pharyngeal pouches and derivatives, developing vertebral column, tail, head and limbs.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.

Experimentally validated
Total	5 [view]
Protein-Protein	5 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	8 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding
GO:0001228	RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0003677	DNA binding
GO:0003700	sequence-specific DNA binding transcription factor activity

Biological Process

GO:0006351	transcription, DNA-templated
GO:0006355	regulation of transcription, DNA-templated
GO:0007492	endoderm development
GO:0009887	organ morphogenesis
GO:0042476	odontogenesis
GO:0042481	regulation of odontogenesis
GO:0045892	negative regulation of transcription, DNA-templated
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0060325	face morphogenesis
GO:0071363	cellular response to growth factor stimulus