InnateDB Protein
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IDBP-141269.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Cdkal1
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Protein Name
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CDK5 regulatory subunit associated protein 1-like 1
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Synonyms
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1190005B03Rik; 6620401C13Rik;
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000089262
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InnateDB Gene
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IDBG-141263 (Cdkal1)
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Protein Structure
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Function |
Catalyzes the methylthiolation of N6- threonylcarbamoyladenosine (t(6)A), leading to the formation of 2- methylthio-N6-threonylcarbamoyladenosine (ms(2)t(6)A) at position 37 in tRNAs that read codons beginning with adenine. {ECO:0000250}.
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Subcellular Localization |
Endoplasmic reticulum membrane {ECO:0000250}; Single-pass membrane protein {ECO:0000250}. Note=Is a tail-anchored protein that exploits the TCR40 assisted pathway for insertion into the endoplasmic reticulum. {ECO:0000250}.
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Disease Associations |
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Tissue Specificity |
Expressed in pancreas, liver and skeletal muscle, especially in white muscle fibers. {ECO:0000269PubMed:23048041}.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Experimentally validated |
Total |
1
[view]
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Protein-Protein |
0
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Protein-DNA |
0
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Protein-RNA |
1
[view]
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Predicted by orthology |
Total |
3 [view]
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
MGI:1921765
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InterPro |
IPR013848
Methylthiotransferase, N-terminal
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PFAM |
PF00919
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q91WE6
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PhosphoSite |
PhosphoSite-Q91WE6
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
68916
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UniGene |
Mm.464293
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RefSeq |
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MGI ID |
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MGI Symbol |
Cdkal1
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OMIM |
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CCDS |
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HPRD |
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IMGT |
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EMBL |
AK004490
AK041864
AK045506
AK082629
AK169761
AL512647
AL513025
AL589701
AL645587
BC016073
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GenPept |
AAH16073
BAB23330
BAC38554
BAE20608
BAE41351
BAE43325
CAI24675
CAI24677
CAI25816
CAI35144
CAI35240
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