Version 5.4
Mus musculus Protein: Exoc2
Summary
InnateDB Protein IDBP-141876.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Exoc2
Protein Name exocyst complex component 2
Synonyms 2410030I24Rik; AI648199; Sec5; Sec5l1;
Species Mus musculus
Ensembl Protein ENSMUSP00000100010
InnateDB Gene IDBG-141872 (Exoc2)
Protein Structure
UniProt Annotation
Function Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. {ECO:0000250}.
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 16 interaction(s) predicted by orthology.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 16 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0017160 Ral GTPase binding
GO:0047485 protein N-terminus binding
Biological Process
GO:0006887 exocytosis
GO:0006893 Golgi to plasma membrane transport
GO:0015031 protein transport
GO:0045921 positive regulation of exocytosis
Cellular Component
GO:0000145 exocyst
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0043231 intracellular membrane-bounded organelle
Protein Structure and Domains
PDB ID MGI:1913732
InterPro IPR002909 IPT domain
IPR014756 Immunoglobulin E-set
PFAM PF01833
PRINTS
PIRSF
SMART SM00429
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9D4H1
PhosphoSite PhosphoSite-Q9D4H1
TrEMBL
UniProt Splice Variant
Entrez Gene 66482
UniGene Mm.293510
RefSeq XP_006516788
MGI ID 1HK6
MGI Symbol Exoc2
OMIM
CCDS CCDS26420
HPRD
IMGT
EMBL AK016532 AK050068 BC048154 BC049102
GenPept AAH48154 AAH49102 BAB30290 BAC34056

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca