Version 5.4
Mus musculus Protein: Il17rb
Summary
InnateDB Protein IDBP-142160.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Il17rb
Protein Name interleukin 17 receptor B
Synonyms Evi27; IL-17ER; IL-17Rh1; Il17br; IL17RH1;
Species Mus musculus
Ensembl Protein ENSMUSP00000016110
InnateDB Gene IDBG-142158 (Il17rb)
Protein Structure
UniProt Annotation
Function Receptor for the proinflammatory cytokines IL17B and IL17E. May play a role in controlling the growth and/or differentiation of hematopoietic cells.
Subcellular Localization Isoform 1: Cell membrane; Single-pass type I membrane protein.Isoform 2: Secreted.
Disease Associations
Tissue Specificity Liver and testis. Expressed at lower level in kidney and lung. Expressed in selected T-cell, B-cell and myeloid cell lines.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
Experimentally validated
Total 3 [view]
Protein-Protein 2 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 6 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004896 cytokine receptor activity
Biological Process
GO:0019221 cytokine-mediated signaling pathway
Cellular Component
GO:0005576 extracellular region
GO:0005737 cytoplasm
GO:0005887 integral component of plasma membrane
GO:0009986 cell surface
Protein Structure and Domains
PDB ID MGI:1355292
InterPro IPR013568 SEFIR
PFAM PF08357
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9JIP3
PhosphoSite PhosphoSite-Q9JIP3
TrEMBL Q543U7
UniProt Splice Variant
Entrez Gene 50905
UniGene Mm.269363
RefSeq NP_062529
MGI ID 3VBC
MGI Symbol Il17rb
OMIM
CCDS CCDS36845
HPRD
IMGT
EMBL AF208108 AF208109 AK045627 BC026546
GenPept AAF86049 AAF86050 AAH26546 BAC32438

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca