Version 5.4
Mus musculus Gene: Il17rb
Summary
InnateDB Gene IDBG-142158.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Il17rb
Gene Name interleukin 17 receptor B
Synonyms Evi27; IL-17ER; IL-17Rh1; Il17br; IL17RH1
Species Mus musculus
Ensembl Gene ENSMUSG00000015966
Encoded Proteins
IDBP-142160
interleukin 17 receptor B
IDBP-401604
interleukin 17 receptor B
IDBP-536430
interleukin 17 receptor B
IDBP-537458
interleukin 17 receptor B
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000056736:
The protein encoded by this gene is a cytokine receptor. This receptor specifically binds to IL17B and IL17E, but does not bind to IL17 and IL17C. This receptor has been shown to mediate the activation of NF-kappaB and the production of IL8 induced by IL17E. The expression of the rat counterpart of this gene was found to be significantly up-regulated during intestinal inflammation, which suggested the immunoregulatory activity of this receptor. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 14:29996141-30008896
Strand Reverse strand
Band B
Transcripts
ENSMUST00000016110 ENSMUSP00000016110
ENSMUST00000122205 ENSMUSP00000113686
ENSMUST00000135888 ENSMUSP00000121407
ENSMUST00000136726 ENSMUSP00000117802
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
Experimentally validated
Total 3 [view]
Protein-Protein 2 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 6 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004896 cytokine receptor activity
Biological Process
GO:0019221 cytokine-mediated signaling pathway
Cellular Component
GO:0005576 extracellular region
GO:0005737 cytoplasm
GO:0005887 integral component of plasma membrane
GO:0009986 cell surface
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000056736
View Gene Order
ENSBTAG00000011178
Not yet available
Pathways
NETPATH
REACTOME
KEGG
mmu04060
Cytokine-cytokine receptor interaction pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
hsa04060
Cytokine-cytokine receptor interaction pathway
INOH
PID NCI
Cross-References
SwissProt Q9JIP3
TrEMBL Q543U7
UniProt Splice Variant
Entrez Gene 50905
UniGene Mm.269363
RefSeq NM_019583 XM_006519244
OMIM
CCDS CCDS36845
HPRD
IMGT
MGI ID MGI:1355292
MGI Symbol Il17rb
EMBL AF208108 AF208109 AK045627 BC026546
GenPept AAF86049 AAF86050 AAH26546 BAC32438
RNA Seq Atlas 50905

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca