Version 5.4
| Mus musculus Protein: Il1f5 | |||||||||||
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| Summary | |||||||||||
| InnateDB Protein | IDBP-142283.6 | ||||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||
| Gene Symbol | Il1f5 | ||||||||||
| Protein Name | interleukin 1 family, member 5 (delta) | ||||||||||
| Synonyms | AI413231; Fil1delta; Il-1h3; Il1hy1; IL36RN; | ||||||||||
| Species | Mus musculus | ||||||||||
| Ensembl Protein | ENSMUSP00000028360 | ||||||||||
| InnateDB Gene | IDBG-142281 (Il1f5) | ||||||||||
| Protein Structure |
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| UniProt Annotation | |||||||||||
| Function | Is a highly and a specific antagonist of the IL-1 receptor-related protein 2/IL1RL2-mediated response to interleukin IL36G. Could constitute part of an independent signaling system analogous to interleukin-1 alpha (IL-1A), beta (IL-1B) receptor agonist and interleukin-1 receptor type I (IL-1R1), that is present in epithelial barriers and takes part in local inflammatory response (By similarity). {ECO:0000250}. | ||||||||||
| Subcellular Localization | Secreted {ECO:0000250}. | ||||||||||
| Disease Associations | |||||||||||
| Tissue Specificity | Highly abundant in embryonic tissue and tissues containing epithelial cells. | ||||||||||
| Comments | |||||||||||
| Interactions | |||||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Protein Structure and Domains | |||||||||||
| PDB ID | MGI:1859325 | ||||||||||
| InterPro |
IPR000975
Interleukin-1 family IPR003294 Interleukin-1 alpha/beta IPR003297 Interleukin-1 receptor antagonist / Interleukin-36 IPR008996 Cytokine, IL-1-like |
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| PFAM |
PF00340
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| PRINTS |
PR00264
PR01357 PR01360 |
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| PIRSF | |||||||||||
| SMART | |||||||||||
| TIGRFAMs | |||||||||||
| Post-translational Modifications | |||||||||||
| Modification | |||||||||||
| Cross-References | |||||||||||
| SwissProt | Q9QYY1 | ||||||||||
| PhosphoSite | PhosphoSite- | ||||||||||
| TrEMBL | A2RTR0 | ||||||||||
| UniProt Splice Variant | |||||||||||
| Entrez Gene | 54450 | ||||||||||
| UniGene | Mm.29261 | ||||||||||
| RefSeq | NP_001139559 | ||||||||||
| MGI ID | 1MD6 | ||||||||||
| MGI Symbol | Il1f5 | ||||||||||
| OMIM | |||||||||||
| CCDS | CCDS50519 | ||||||||||
| HPRD | |||||||||||
| IMGT | |||||||||||
| EMBL | AF200495 AF230378 AJ250429 AK008977 AK009741 AL732430 BC132600 BC132602 | ||||||||||
| GenPept | AAF69251 AAF91275 AAI32601 AAI32603 BAB26002 BAB26471 CAB59831 | ||||||||||