Version 5.4
Mus musculus Gene: Il1f5
Summary
InnateDB Gene IDBG-142281.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Il1f5
Gene Name interleukin 1 family, member 5 (delta)
Synonyms AI413231; Fil1delta; Il-1h3; Il1hy1; IL36RN
Species Mus musculus
Ensembl Gene ENSMUSG00000026983
Encoded Proteins
IDBP-142283
interleukin 1 family, member 5 (delta)
IDBP-251658
interleukin 1 family, member 5 (delta)
IDBP-532881
interleukin 1 family, member 5 (delta)
IDBP-621848
interleukin 1 family, member 5 (delta)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000136695:
The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine was shown to specifically inhibit the activation of NF-kappaB induced by interleukin 1 family, member 6 (IL1F6). This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. Two alternatively spliced transcript variants encoding the same protein have been reported. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 2:24276954-24283426
Strand Forward strand
Band A3
Transcripts
ENSMUST00000028360 ENSMUSP00000028360
ENSMUST00000114490 ENSMUSP00000110134
ENSMUST00000123053 ENSMUSP00000116122
ENSMUST00000147885
ENSMUST00000123577
ENSMUST00000168941 ENSMUSP00000126028
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Predicted by orthology
Total 5 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0005125 cytokine activity
GO:0005149 interleukin-1 receptor binding
GO:0005152 interleukin-1 receptor antagonist activity
Biological Process
GO:0001960 negative regulation of cytokine-mediated signaling pathway
GO:0032715 negative regulation of interleukin-6 production
Cellular Component
GO:0005615 extracellular space
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000136695
View Gene Order
ENSBTAG00000039839
Not yet available
Cross-References
SwissProt Q9QYY1
TrEMBL A2AIA8 A2RTR0
UniProt Splice Variant
Entrez Gene 54450
UniGene Mm.29261
RefSeq NM_001146088 NM_001146087 NM_019451
OMIM
CCDS CCDS50519
HPRD
IMGT
MGI ID MGI:1859325
MGI Symbol Il1f5
EMBL AF200495 AF230378 AJ250429 AK008977 AK009741 AL732430 BC132600 BC132602
GenPept AAF69251 AAF91275 AAI32601 AAI32603 BAB26002 BAB26471 CAB59831
RNA Seq Atlas 54450

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca