Version 5.4
Mus musculus Protein: Slc34a3
Summary
InnateDB Protein IDBP-144405.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Slc34a3
Protein Name solute carrier family 34 (sodium phosphate), member 3
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000006638
InnateDB Gene IDBG-144403 (Slc34a3)
Protein Structure
UniProt Annotation
Function May be involved in actively transporting phosphate into cells via Na(+) cotransport in the renal brush border membrane. Probably mediates 20-30% of the apical influx.
Subcellular Localization Membrane; Multi-pass membrane protein.
Disease Associations
Tissue Specificity Observed only in kidney.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005436 sodium:phosphate symporter activity
GO:0015321 sodium-dependent phosphate transmembrane transporter activity
Biological Process
GO:0006814 sodium ion transport
GO:0006817 phosphate ion transport
GO:0030643 cellular phosphate ion homeostasis
GO:0035435 phosphate ion transmembrane transport
GO:0035725 sodium ion transmembrane transport
GO:0044341 sodium-dependent phosphate transport
Cellular Component
GO:0005903 brush border
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0016324 apical plasma membrane
Protein Structure and Domains
PDB ID MGI:2159410
InterPro IPR003841 Sodium-dependent phosphate transport protein
PFAM PF02690
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q80SU6
PhosphoSite PhosphoSite-Q80SU6
TrEMBL
UniProt Splice Variant
Entrez Gene 142681
UniGene Mm.490356
RefSeq NP_543130
MGI ID
MGI Symbol Slc34a3
OMIM
CCDS CCDS15754
HPRD
IMGT
EMBL AB054999 AB080134 AL732309 BC125326 BC131997 CH466542
GenPept AAI25327 AAI31998 BAB83241 BAC55069 CAM14672 EDL08215 EDL08216

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca