Mus musculus Gene: Slc34a3
Summary
InnateDB Gene IDBG-144403.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Slc34a3
Gene Name solute carrier family 34 (sodium phosphate), member 3
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000006469
Encoded Proteins
solute carrier family 34 (sodium phosphate), member 3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000198569:
This gene encodes a member of SLC34A transporter family of proteins, and is expressed primarily in the kidney. It is involved in transporting phosphate into cells via sodium cotransport in the renal brush border membrane, and contributes to the maintenance of inorganic phosphate concentration in the kidney. Mutations in this gene are associated with hereditary hypophosphatemic rickets with hypercalciuria. Alternatively spliced transcript variants varying in the 5' UTR have been found for this gene.[provided by RefSeq, Apr 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 2:25228898-25234364
Strand Reverse strand
Band A3
Transcripts
ENSMUST00000006638 ENSMUSP00000006638
ENSMUST00000124146
ENSMUST00000155420
ENSMUST00000144884
ENSMUST00000137482
ENSMUST00000152997
ENSMUST00000142095
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005436 sodium:phosphate symporter activity
GO:0015321 sodium-dependent phosphate transmembrane transporter activity
Biological Process
GO:0006814 sodium ion transport
GO:0006817 phosphate ion transport
GO:0030643 cellular phosphate ion homeostasis
GO:0035435 phosphate ion transmembrane transport
GO:0035725 sodium ion transmembrane transport
GO:0044341 sodium-dependent phosphate transport
Cellular Component
GO:0005903 brush border
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0016324 apical plasma membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Not yet available
Pathways
NETPATH
REACTOME
SLC-mediated transmembrane transport pathway
Transport of inorganic cations/anions and amino acids/oligopeptides pathway
Transmembrane transport of small molecules pathway
Type II Na+/Pi cotransporters pathway
Sodium-coupled phosphate cotransporters pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Type II Na+/Pi cotransporters pathway
Sodium-coupled phosphate cotransporters pathway
Transport of inorganic cations/anions and amino acids/oligopeptides pathway
Transmembrane transport of small molecules pathway
SLC-mediated transmembrane transport pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.490356
RefSeq NM_080854 XM_006497677 XM_006497678 XM_006497679
OMIM
CCDS CCDS15754
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas