InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Lig1

Summary

InnateDB Protein

IDBP-144446.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Lig1

Protein Name

ligase I, DNA, ATP-dependent

Synonyms

AL033288; LigI;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000096411

InnateDB Gene

IDBG-144442 (Lig1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.

Experimentally validated
Total	1 [view]
Protein-Protein	1 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	9 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003677	DNA binding
GO:0003910	DNA ligase (ATP) activity
GO:0005524	ATP binding

Biological Process

GO:0006260	DNA replication
GO:0006266	DNA ligation
GO:0006273	lagging strand elongation
GO:0006281	DNA repair
GO:0006303	double-strand break repair via nonhomologous end joining
GO:0006310	DNA recombination
GO:0042542	response to hydrogen peroxide
GO:0071897	DNA biosynthetic process

Cellular Component

GO:0005634	nucleus
GO:0005694	chromosome
GO:0005739	mitochondrion

Protein Structure and Domains

PDB ID

MGI:101789

InterPro

IPR000977 DNA ligase, ATP-dependent
IPR012308 DNA ligase, ATP-dependent, N-terminal
IPR012309 DNA ligase, ATP-dependent, C-terminal
IPR012310 DNA ligase, ATP-dependent, central
IPR012340 Nucleic acid-binding, OB-fold

PFAM

PF04675
PF04679
PF01068

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-