Version 5.4
Homo sapiens Protein: CCNB2
Summary
InnateDB Protein IDBP-14458.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CCNB2
Protein Name cyclin B2
Synonyms HsT17299;
Species Homo sapiens
Ensembl Protein ENSP00000288207
InnateDB Gene IDBG-14456 (CCNB2)
Protein Structure
UniProt Annotation
Function Essential for the control of the cell cycle at the G2/M (mitosis) transition.
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 33 experimentally validated interaction(s) in this database.
Experimentally validated
Total 33 [view]
Protein-Protein 31 [view]
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0019901 protein kinase binding
Biological Process
GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity
GO:0000086 G2/M transition of mitotic cell cycle
GO:0000278 mitotic cell cycle
GO:0001701 in utero embryonic development
GO:0007067 mitotic nuclear division
GO:0007077 mitotic nuclear envelope disassembly
GO:0040007 growth
GO:0043029 T cell homeostasis
GO:0048538 thymus development
GO:0051726 regulation of cell cycle
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005813 centrosome
GO:0005829 cytosol
GO:0015630 microtubule cytoskeleton
GO:0016020 membrane
Protein Structure and Domains
PDB ID
InterPro IPR004367 Cyclin, C-terminal domain
IPR006671 Cyclin, N-terminal
IPR013763 Cyclin-like
IPR014400 Cyclin A/B/D/E/F
PFAM PF02984
PF00134
PRINTS
PIRSF PIRSF001771
SMART SM00385
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt O95067
PhosphoSite PhosphoSite-O95067
TrEMBL
UniProt Splice Variant
Entrez Gene 9133
UniGene
RefSeq NP_004692
HUGO HGNC:1580
OMIM 602755
CCDS CCDS10170
HPRD 04131
IMGT
EMBL AB020981 AF002822 AK001404 AL080146 AY864066 BC105086 BC105112 CH471082 CR533527
GenPept AAD09309 AAI05087 AAI05113 AAW34361 BAA78387 BAG50905 CAB45739 CAG38558 EAW77563

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca