InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Prss21

Summary

InnateDB Protein

IDBP-144772.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Prss21

Protein Name

protease, serine, 21

Synonyms

1700023E12Rik; mT4; TESP5; testisin;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000024928

InnateDB Gene

IDBG-144770 (Prss21)

Protein Structure

UniProt Annotation

Function

Could regulate proteolytic events associated with testicular germ cell maturation.

Subcellular Localization

Cell membrane {ECO:0000305}; Lipid-anchor, GPI-anchor {ECO:0000305}.

Disease Associations

Tissue Specificity

Testis.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003824	catalytic activity
GO:0004252	serine-type endopeptidase activity
GO:0005515	protein binding
GO:0008236	serine-type peptidase activity

Biological Process

GO:0006508	proteolysis
GO:0007283	spermatogenesis

Cellular Component

GO:0005737	cytoplasm
GO:0005886	plasma membrane
GO:0016020	membrane
GO:0031225	anchored component of membrane

Protein Structure and Domains

PDB ID

MGI:1916698

InterPro

IPR001254 Peptidase S1
IPR001314 Peptidase S1A, chymotrypsin-type
IPR009003 Trypsin-like cysteine/serine peptidase domain
IPR015420 Peptidase S1A, nudel

PFAM

PF00089
PF09342

PRINTS

PR00722

PIRSF

SMART

SM00020

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt