Version 5.4
Mus musculus Gene: Prss21
Summary
InnateDB Gene IDBG-144770.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Prss21
Gene Name protease, serine, 21
Synonyms 1700023E12Rik; mT4; TESP5; testisin
Species Mus musculus
Ensembl Gene ENSMUSG00000024116
Encoded Proteins
IDBP-144772
protease, serine, 21
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000007038:
This gene encodes a cell-surface anchored serine protease, which is a member of the trypsin family of serine proteases. The encoded protein is predicted to be active on peptide linkages involving the carboxyl group of lysine or arginine. The encoded protein localizes to the cytoplasm and the plasma membrane of premeiotic testicular germ cells and may be involved in progression of testicular tumors of germ cell origin. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jul 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 17:23868056-23873114
Strand Forward strand
Band A3.3
Transcripts
ENSMUST00000024928 ENSMUSP00000024928
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003824 catalytic activity
GO:0004252 serine-type endopeptidase activity
GO:0005515 protein binding
GO:0008236 serine-type peptidase activity
Biological Process
GO:0006508 proteolysis
GO:0007283 spermatogenesis
Cellular Component
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0031225 anchored component of membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000007038
View Gene Order
ENSBTAG00000015045
Not yet available
Cross-References
SwissProt Q9JHJ7
TrEMBL Q54AE4 Q80YD8
UniProt Splice Variant
Entrez Gene 57256
UniGene Mm.386785
RefSeq NM_020487
OMIM
CCDS CCDS28468
HPRD
IMGT
MGI ID MGI:1916698
MGI Symbol Prss21
EMBL AB033822 AB041645 AB059414 AB059415 AF176209 AF226710 AF304012 AK006271 AY005145 BC049588 BC116755 BC116757 CH466606
GenPept AAF64407 AAF64428 AAG02255 AAH49588 AAI16756 AAI16758 AAK29360 BAB16701 BAB61787 BAB61788 BAB64263 EDL22281
RNA Seq Atlas 57256

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca