InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: 2610018G03Rik

Summary

InnateDB Protein

IDBP-144891.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

2610018G03Rik

Protein Name

RIKEN cDNA 2610018G03 gene

Synonyms

2610018G03Rik; Mst4;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000033444

InnateDB Gene

IDBG-144889 (2610018G03Rik)

Protein Structure

UniProt Annotation

Function

Mediator of cell growth. Modulates apoptosis (By similarity). {ECO:0000250}.

Subcellular Localization

Cytoplasm {ECO:0000250}. Golgi apparatus membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Note=Localizes to the Golgi apparatus. {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 32 interaction(s) predicted by orthology.

Experimentally validated
Total	2 [view]
Protein-Protein	2 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	32 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000287	magnesium ion binding
GO:0004672	protein kinase activity
GO:0004702	receptor signaling protein serine/threonine kinase activity
GO:0004713	protein tyrosine kinase activity
GO:0005515	protein binding
GO:0005524	ATP binding
GO:0016772	transferase activity, transferring phosphorus-containing groups
GO:0042802	identical protein binding

Biological Process

GO:0006468	protein phosphorylation
GO:0006915	apoptotic process
GO:0023014	signal transduction by phosphorylation
GO:0035556	intracellular signal transduction
GO:0042981	regulation of apoptotic process
GO:0045595	regulation of cell differentiation

Cellular Component

GO:0000139	Golgi membrane
GO:0005634	nucleus
GO:0005737	cytoplasm
GO:0005794	Golgi apparatus
GO:0005813	centrosome

Protein Structure and Domains

PDB ID

MGI:1917665

InterPro

IPR000719 Protein kinase domain
IPR001245 Serine-threonine/tyrosine-protein kinase catalytic domain
IPR002290 Serine/threonine- /dual specificity protein kinase, catalytic domain
IPR011009 Protein kinase-like domain
IPR020635 Tyrosine-protein kinase, catalytic domain

PFAM

PF00069
PF07714

PRINTS

PR00109

PIRSF

SMART

SM00220
SM00219

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt