InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Ccna1

Summary

InnateDB Protein

IDBP-145076.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Ccna1

Protein Name

cyclin A1

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000029368

InnateDB Gene

IDBG-145074 (Ccna1)

Protein Structure

UniProt Annotation

Function

May be involved in the control of the cell cycle at the G1/S (start) and G2/M (mitosis) transitions. May primarily function in the control of the germline meiotic cell cycle and additionally in the control of mitotic cell cycle in some somatic cells. {ECO:0000269PubMed:10068472, ECO:0000269PubMed:9843212}.

Subcellular Localization

Nucleus {ECO:0000250}. Cytoplasm, cytoskeleton, spindle. Note=In oocytes at least, it associates with the spindle during metaphase.

Disease Associations

Tissue Specificity

Testis and ovaries.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 76 interaction(s) predicted by orthology.

Experimentally validated
Total	3 [view]
Protein-Protein	3 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	76 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0019901	protein kinase binding

Biological Process

GO:0000079	regulation of cyclin-dependent protein serine/threonine kinase activity
GO:0007067	mitotic nuclear division
GO:0007126	meiotic nuclear division
GO:0007275	multicellular organismal development
GO:0007283	spermatogenesis
GO:0010389	regulation of G2/M transition of mitotic cell cycle
GO:0030154	cell differentiation
GO:0051726	regulation of cell cycle