InnateDB Protein
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IDBP-145120.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Pggt1b
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Protein Name
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protein geranylgeranyltransferase type I, beta subunit
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Synonyms
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000025354
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InnateDB Gene
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IDBG-145118 (Pggt1b)
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Protein Structure
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Function |
Catalyzes the transfer of a geranyl-geranyl moiety from geranyl-geranyl pyrophosphate to a cysteine at the fourth position from the C-terminus of proteins having the C-terminal sequence Cys-aliphatic-aliphatic-X. Known substrates include RAC1, RAC2, RAP1A and RAP1B (By similarity). {ECO:0000250}.
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Subcellular Localization |
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
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Predicted by orthology |
Total |
1 [view]
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Molecular Function |
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Biological Process |
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Cellular Component |
GO:0005953
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CAAX-protein geranylgeranyltransferase complex
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PDB ID |
MGI:1917514
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InterPro |
IPR001330
Prenyltransferase/squalene oxidase
IPR008930
Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid
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PFAM |
PF00432
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q8BUY9
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PhosphoSite |
PhosphoSite-Q8BUY9
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TrEMBL |
Q05BF8
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UniProt Splice Variant |
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Entrez Gene |
225467
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UniGene |
Mm.419521
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RefSeq |
NP_766215
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MGI ID |
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MGI Symbol |
Pggt1b
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OMIM |
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CCDS |
CCDS29230
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HPRD |
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IMGT |
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EMBL |
AK081731
BC048404
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GenPept |
AAH48404
BAC38314
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