InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Spg20

Summary

InnateDB Protein

IDBP-145166.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Spg20

Protein Name

spastic paraplegia 20, spartin (Troyer syndrome) homolog (human)

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000042367

InnateDB Gene

IDBG-145164 (Spg20)

Protein Structure

UniProt Annotation

Function

May be implicated in endosomal trafficking, or microtubule dynamics, or both.

Subcellular Localization

Cytoplasm {ECO:0000250}. Note=Transiently associated with endosomes. {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 32 interaction(s) predicted by orthology.

Experimentally validated
Total	2 [view]
Protein-Protein	1 [view]
Protein-DNA	0
Protein-RNA	1 [view]
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	32 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0031625	ubiquitin protein ligase binding

Biological Process

GO:0009838	abscission
GO:0030514	negative regulation of BMP signaling pathway
GO:0034389	lipid particle organization
GO:0048698	negative regulation of collateral sprouting in absence of injury
GO:0050905	neuromuscular process
GO:0051301	cell division
GO:0051881	regulation of mitochondrial membrane potential
GO:0060612	adipose tissue development