InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Adcy8

Summary

InnateDB Protein

IDBP-145295.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Adcy8

Protein Name

adenylate cyclase 8

Synonyms

AC8; AW060868;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000023007

InnateDB Gene

IDBG-145293 (Adcy8)

Protein Structure

UniProt Annotation

Function

This is a membrane-bound, calcium-stimulable adenylyl cyclase. May be involved in learning, in memory and in drug dependence (By similarity). {ECO:0000250}.

Subcellular Localization

Membrane; Multi-pass membrane protein.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Experimentally validated
Total	4 [view]
Protein-Protein	4 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004016	adenylate cyclase activity
GO:0005524	ATP binding
GO:0016849	phosphorus-oxygen lyase activity
GO:0046872	metal ion binding

Biological Process

GO:0006171	cAMP biosynthetic process
GO:0007616	long-term memory
GO:0009190	cyclic nucleotide biosynthetic process
GO:0035556	intracellular signal transduction