Version 5.4
Mus musculus Protein: Abca2
Summary
InnateDB Protein IDBP-145760.5
Last Modified 2012-02-14 [Report errors or provide feedback]
Gene Symbol Abca2
Protein Name ATP-binding cassette, sub-family A (ABC1), member 2
Synonyms Abc2; AI413825; D2H0S1474E; mKIAA1062;
Species Mus musculus
Ensembl Protein ENSMUSP00000099983
InnateDB Gene IDBG-145758 (Abca2)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0005524 ATP binding
GO:0016887 ATPase activity
GO:0017111 nucleoside-triphosphatase activity
Biological Process
GO:0006200 ATP catabolic process
GO:0006357 regulation of transcription from RNA polymerase II promoter
GO:0032383 regulation of intracellular cholesterol transport
GO:0042632 cholesterol homeostasis
GO:0048545 response to steroid hormone
Cellular Component
GO:0005764 lysosome
GO:0005768 endosome
GO:0016020 membrane
Protein Structure and Domains
PDB ID MGI:99606
InterPro IPR003439 ABC transporter-like
IPR003593 AAA+ ATPase domain
IPR027417 P-loop containing nucleoside triphosphate hydrolase
PFAM PF00005
PRINTS
PIRSF
SMART SM00382
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q6ZPZ4
UniProt Splice Variant
Entrez Gene 11305
UniGene Mm.418609
RefSeq NP_031405
MGI ID
MGI Symbol Abca2
OMIM
CCDS CCDS15773
HPRD
IMGT
EMBL AK129274 AK157769 AK165788 AL732557 CH466542
GenPept BAC98084 BAE34188 BAE38380 EDL08245

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca