Version 5.4
| Mus musculus Gene: Abca2 | |||||||||||||||
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| Summary | |||||||||||||||
| InnateDB Gene | IDBG-145758.6 | ||||||||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||
| Gene Symbol | Abca2 | ||||||||||||||
| Gene Name | ATP-binding cassette, sub-family A (ABC1), member 2 | ||||||||||||||
| Synonyms | Abc2; AI413825; D2H0S1474E; mKIAA1062 | ||||||||||||||
| Species | Mus musculus | ||||||||||||||
| Ensembl Gene | ENSMUSG00000026944 | ||||||||||||||
| Encoded Proteins |
ATP-binding cassette, sub-family A (ABC1), member 2
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| Protein Structure | |||||||||||||||
| Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||
| Entrez Gene | |||||||||||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000107331:
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. This protein is highly expressed in brain tissue and may play a role in macrophage lipid metabolism and neural development. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
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| Gene Information | |||||||||||||||
| Type | Protein coding | ||||||||||||||
| Genomic Location | Chromosome 2:25428703-25448540 | ||||||||||||||
| Strand | Forward strand | ||||||||||||||
| Band | A3 | ||||||||||||||
| Transcripts |
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| Interactions | |||||||||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||||||||
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Species
Homo sapiens
Bos taurus
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Gene ID
Gene Order
Not yet available
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| Pathways | |||||||||||||||
| NETPATH | |||||||||||||||
| REACTOME | |||||||||||||||
| KEGG |
ABC transporters pathway
Lysosome pathway
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| INOH | |||||||||||||||
| PID NCI | |||||||||||||||
| Pathway Predictions based on Human Orthology Data | |||||||||||||||
| NETPATH | |||||||||||||||
| REACTOME |
ABCA transporters in lipid homeostasis pathway
ABC-family proteins mediated transport pathway
Transmembrane transport of small molecules pathway
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| KEGG |
ABC transporters pathway
Lysosome pathway
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| INOH | |||||||||||||||
| PID NCI | |||||||||||||||
| Cross-References | |||||||||||||||
| SwissProt | |||||||||||||||
| TrEMBL | A2AJ26 Q3TMR1 Q3TZM0 Q6ZPZ4 | ||||||||||||||
| UniProt Splice Variant | |||||||||||||||
| Entrez Gene | 11305 | ||||||||||||||
| UniGene | Mm.2210 Mm.418609 | ||||||||||||||
| RefSeq | NM_007379 XM_006497609 XM_006497610 XM_006497612 XM_006497613 XM_006497614 XM_006497615 XM_006497616 | ||||||||||||||
| OMIM | |||||||||||||||
| CCDS | CCDS15773 | ||||||||||||||
| HPRD | |||||||||||||||
| IMGT | |||||||||||||||
| MGI ID | MGI:99606 | ||||||||||||||
| MGI Symbol | Abca2 | ||||||||||||||
| EMBL | AK129274 AK157769 AK165788 AL732557 CH466542 | ||||||||||||||
| GenPept | BAC98084 BAE34188 BAE38380 EDL08245 | ||||||||||||||
| RNA Seq Atlas | 11305 | ||||||||||||||