InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Clcn2

Summary

InnateDB Protein

IDBP-146156.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Clcn2

Protein Name

chloride channel 2

Synonyms

AL118368; ClC-2; Clc2; nmf240;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000007207

InnateDB Gene

IDBG-146154 (Clcn2)

Protein Structure

UniProt Annotation

Function

Voltage-gated chloride channel. Chloride channels have several functions including the regulation of cell volume; membrane potential stabilization, signal transduction and transepithelial transport.

Subcellular Localization

Membrane; Multi-pass membrane protein.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.

Predicted by orthology
Total	3 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005216	ion channel activity
GO:0005247	voltage-gated chloride channel activity
GO:0030554	adenyl nucleotide binding

Biological Process

GO:0006821	chloride transport
GO:0034765	regulation of ion transmembrane transport
GO:0044070	regulation of anion transport
GO:0055085	transmembrane transport
GO:0060041	retina development in camera-type eye
GO:0060689	cell differentiation involved in salivary gland development
GO:1902476	chloride transmembrane transport