Version 5.4
Mus musculus Protein: Phpt1
Summary
InnateDB Protein IDBP-146494.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Phpt1
Protein Name phosphohistidine phosphatase 1
Synonyms 1700008C22Rik; Php14;
Species Mus musculus
Ensembl Protein ENSMUSP00000037417
InnateDB Gene IDBG-146492 (Phpt1)
Protein Structure
UniProt Annotation
Function Exhibits phosphohistidine phosphatase activity. {ECO:0000250}.
Subcellular Localization Cytoplasm {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 13 interaction(s) predicted by orthology.
Predicted by orthology
Total 13 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004721 phosphoprotein phosphatase activity
GO:0008969 phosphohistidine phosphatase activity
GO:0019855 calcium channel inhibitor activity
GO:0044325 ion channel binding
Biological Process
GO:0006470 protein dephosphorylation
GO:0035774 positive regulation of insulin secretion involved in cellular response to glucose stimulus
GO:0035971 peptidyl-histidine dephosphorylation
GO:0050860 negative regulation of T cell receptor signaling pathway
GO:0051350 negative regulation of lyase activity
GO:2000147 positive regulation of cell motility
GO:2000249 regulation of actin cytoskeleton reorganization
GO:2000984 negative regulation of ATP citrate synthase activity
Cellular Component
GO:0005829 cytosol
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID MGI:1922704
InterPro IPR007702 Janus
PFAM PF05005
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9DAK9
PhosphoSite PhosphoSite-Q9DAK9
TrEMBL
UniProt Splice Variant
Entrez Gene 75454
UniGene
RefSeq NP_083569
MGI ID
MGI Symbol Phpt1
OMIM
CCDS CCDS15781
HPRD
IMGT
EMBL AK005756 BC028657
GenPept AAH28657 BAB24222

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca