InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Rabl6

Summary

InnateDB Protein

IDBP-146546.7

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Rabl6

Protein Name

RIKEN cDNA B230208H17 gene

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000058746

InnateDB Gene

IDBG-146544 (Rabl6)

Protein Structure

UniProt Annotation

Function

May enhance cellular proliferation. May reduce growth inhibitory activity of CDKN2A (By similarity). {ECO:0000250}.

Subcellular Localization

Nucleus {ECO:0000305}. Cytoplasm. Note=Predominantly cytoplasmic. Proposed to shuttle between cytoplasm and nucleus (By similarity). {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.

Experimentally validated
Total	2 [view]
Protein-Protein	2 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	9 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0005525	GTP binding

Biological Process

GO:0007264	small GTPase mediated signal transduction
GO:0015031	protein transport

Cellular Component

GO:0005622	intracellular
GO:0005634	nucleus
GO:0005737	cytoplasm
GO:0005813	centrosome

Protein Structure and Domains

PDB ID

MGI:2442633

InterPro

IPR001806 Small GTPase superfamily
IPR003579 Small GTPase superfamily, Rab type
IPR006689 Small GTPase superfamily, ARF/SAR type
IPR013684 Mitochondrial Rho-like
IPR027417 P-loop containing nucleoside triphosphate hydrolase

PFAM

PF00071
PF00025
PF08477

PRINTS

PR00449
PR00328

PIRSF

SMART

SM00175

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt