Version 5.4
Mus musculus Protein: Calcoco2
Summary
InnateDB Protein IDBP-146604.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Calcoco2
Protein Name calcium binding and coiled-coil domain 2
Synonyms 2410154J16Rik; C77254; Ndp52; Ndp52l1;
Species Mus musculus
Ensembl Protein ENSMUSP00000087407
InnateDB Gene IDBG-209835 (Calcoco2)
Protein Structure
UniProt Annotation
Function May play a role in ruffle formation and actin cytoskeleton organization. Seems to negatively regulate constitutive secretion (By similarity). {ECO:0000250}.
Subcellular Localization Cytoplasm, perinuclear region {ECO:0000250}. Golgi apparatus {ECO:0000250}. Cytoplasm, cytoskeleton {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 70 interaction(s) predicted by orthology.
Predicted by orthology
Total 70 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0042803 protein homodimerization activity
Biological Process
GO:0034341 response to interferon-gamma
GO:0045087 innate immune response (InnateDB)
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005794 Golgi apparatus
GO:0005856 cytoskeleton
GO:0016020 membrane
GO:0043231 intracellular membrane-bounded organelle
GO:0048471 perinuclear region of cytoplasm
Protein Structure and Domains
PDB ID MGI:1343177
InterPro IPR012852 Coiled-coil transcriptional coactivator-like
PFAM PF07888
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt A2A6M5
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 76815
UniGene Mm.296049
RefSeq NP_001257947
MGI ID
MGI Symbol Calcoco2
OMIM
CCDS CCDS59567
HPRD
IMGT
EMBL AF490344 AK010816 AK166710 AK166756 AK167172 AL603682
GenPept AAO84502 BAB27200 BAE38963 BAE38997 BAE39309 CAM18272

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca