Version 5.4
Mus musculus Protein: Sesn1
Summary
InnateDB Protein IDBP-147081.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Sesn1
Protein Name sestrin 1
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000043034
InnateDB Gene IDBG-147077 (Sesn1)
Protein Structure
UniProt Annotation
Function Involved in the reduction of peroxiredoxins. {ECO:0000250}.
Subcellular Localization Nucleus {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Predicted by orthology
Total 5 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
Biological Process
GO:0051896 regulation of protein kinase B signaling
GO:1901031 regulation of response to reactive oxygen species
Cellular Component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID MGI:2155278
InterPro IPR006730 Sestrin
IPR029032 AhpD-like
PFAM PF04636
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P58006
PhosphoSite PhosphoSite-P58006
TrEMBL
UniProt Splice Variant
Entrez Gene 140742
UniGene Mm.415868
RefSeq NP_001013388
MGI ID
MGI Symbol Sesn1
OMIM
CCDS CCDS23809
HPRD
IMGT
EMBL AC115297 AC165442 BC055753
GenPept AAH55753

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca