InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Traf7

Summary

InnateDB Protein

IDBP-147100.5

Last Modified

2012-02-14 [Report errors or provide feedback]

Gene Symbol

Traf7

Protein Name

TNF receptor-associated factor 7

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000069334

InnateDB Gene

IDBG-147098 (Traf7)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.

Experimentally validated
Total	4 [view]
Protein-Protein	4 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	8 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004842	ubiquitin-protein transferase activity
GO:0005515	protein binding
GO:0008270	zinc ion binding

Biological Process

GO:0006915	apoptotic process
GO:0016567	protein ubiquitination
GO:0043410	positive regulation of MAPK cascade

Cellular Component

Protein Structure and Domains

PDB ID

MGI:3042141

InterPro

IPR001680 WD40 repeat
IPR001841 Zinc finger, RING-type
IPR008974 TRAF-like
IPR017986 WD40-repeat-containing domain
IPR020472 G-protein beta WD-40 repeat

PFAM

PF00400
PF13639
PF14634

PRINTS

PR00320

PIRSF

SMART

SM00320
SM00184

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt