InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Ppp5c

Summary

InnateDB Protein

IDBP-147418.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Ppp5c

Protein Name

protein phosphatase 5, catalytic subunit

Synonyms

AU020526; PP5;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000003183

InnateDB Gene

IDBG-147416 (Ppp5c)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 14 experimentally validated interaction(s) in this database.
They are also associated with 39 interaction(s) predicted by orthology.

Experimentally validated
Total	14 [view]
Protein-Protein	14 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	39 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003723	RNA binding
GO:0004721	phosphoprotein phosphatase activity
GO:0004871	signal transducer activity
GO:0005515	protein binding
GO:0016787	hydrolase activity
GO:0042802	identical protein binding
GO:0046872	metal ion binding

Biological Process

GO:0006470	protein dephosphorylation
GO:0007165	signal transduction
GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043278	response to morphine
GO:0051291	protein heterooligomerization

Cellular Component

GO:0005634	nucleus
GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0016020	membrane
GO:0043005	neuron projection
GO:0043025	neuronal cell body
GO:0043231	intracellular membrane-bounded organelle

Protein Structure and Domains

PDB ID

MGI:102666

InterPro

IPR001440 Tetratricopeptide TPR1
IPR004843 Calcineurin-like phosphoesterase domain, apaH type
IPR006186 Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase
IPR011236 Serine/threonine protein phosphatase 5
IPR013026 Tetratricopeptide repeat-containing domain
IPR013105 Tetratricopeptide TPR2
IPR013235 PPP domain
IPR019734 Tetratricopeptide repeat
IPR029052 Metallo-dependent phosphatase-like

PFAM