InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Ehhadh

Summary

InnateDB Protein

IDBP-147439.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Ehhadh

Protein Name

enoyl-Coenzyme A, hydratase/3-hydroxyacyl Coenzyme A dehydrogenase

Synonyms

1300002P22Rik; HD; L-PBE; LBFP; LBP; MFP; MFP1; PBFE;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000023559

InnateDB Gene

IDBG-147437 (Ehhadh)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Peroxisome {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.

Experimentally validated
Total	8 [view]
Protein-Protein	8 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	3 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003824	catalytic activity
GO:0003857	3-hydroxyacyl-CoA dehydrogenase activity
GO:0004165	dodecenoyl-CoA delta-isomerase activity
GO:0004300	enoyl-CoA hydratase activity
GO:0005102	receptor binding
GO:0016491	oxidoreductase activity
GO:0019899	enzyme binding
GO:0050662	coenzyme binding

Biological Process

GO:0006475	internal protein amino acid acetylation
GO:0006631	fatty acid metabolic process
GO:0006635	fatty acid beta-oxidation
GO:0006637	acyl-CoA metabolic process
GO:0008152	metabolic process
GO:0055114	oxidation-reduction process

Cellular Component

GO:0005634	nucleus
GO:0005737	cytoplasm
GO:0005739	mitochondrion
GO:0005777	peroxisome
GO:0005829	cytosol
GO:0043231	intracellular membrane-bounded organelle

Protein Structure and Domains

PDB ID

MGI:1277964

InterPro

IPR001753 Crotonase superfamily
IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal
IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding
IPR008927 6-phosphogluconate dehydrogenase, C-terminal-like
IPR029045 ClpP/crotonase-like domain

PFAM

PF00378
PF00725
PF02737

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q9DBM2

PhosphoSite