Version 5.4
Mus musculus Protein: Ppm1g
Summary
InnateDB Protein IDBP-148400.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ppm1g
Protein Name protein phosphatase 1G (formerly 2C), magnesium-dependent, gamma isoform
Synonyms AI385652; Fin13;
Species Mus musculus
Ensembl Protein ENSMUSP00000031032
InnateDB Gene IDBG-148398 (Ppm1g)
Protein Structure
UniProt Annotation
Function May be involved in regulation of cell cycle. {ECO:0000269PubMed:9271424}.
Subcellular Localization Nucleus {ECO:0000269PubMed:9271424}.
Disease Associations
Tissue Specificity Highly expressed in testis. Low level of expression in kidney. Also expressed in a number of tissues undergoing proliferation including embryo, uterus at pregnancy, placenta, and ovaries.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 39 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 39 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003824 catalytic activity
GO:0004721 phosphoprotein phosphatase activity
GO:0004722 protein serine/threonine phosphatase activity
GO:0005515 protein binding
GO:0046872 metal ion binding
Biological Process
GO:0006470 protein dephosphorylation
GO:0007050 cell cycle arrest
GO:0035970 peptidyl-threonine dephosphorylation
Cellular Component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID MGI:106065
InterPro IPR001932 Protein phosphatase 2C (PP2C)-like domain
PFAM PF00481
PF07228
PRINTS
PIRSF
SMART SM00331
SM00332
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q61074
PhosphoSite PhosphoSite-Q61074
TrEMBL
UniProt Splice Variant
Entrez Gene 14208
UniGene Mm.14501
RefSeq NP_032040
MGI ID
MGI Symbol Ppm1g
OMIM
CCDS CCDS19179
HPRD
IMGT
EMBL BC009004 U42383
GenPept AAC26322 AAH09004

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca