Version 5.4
Mus musculus Gene: Ppm1g
Summary
InnateDB Gene IDBG-148398.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ppm1g
Gene Name protein phosphatase 1G (formerly 2C), magnesium-dependent, gamma isoform
Synonyms AI385652; Fin13
Species Mus musculus
Ensembl Gene ENSMUSG00000029147
Encoded Proteins
IDBP-148400
protein phosphatase 1G (formerly 2C), magnesium-dependent, gamma isoform
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000115241:
The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase is found to be responsible for the dephosphorylation of Pre-mRNA splicing factors, which is important for the formation of functional spliceosome. Studies of a similar gene in mice suggested a role of this phosphatase in regulating cell cycle progression. [provided by RefSeq, Apr 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 5:31202668-31220545
Strand Reverse strand
Band B1
Transcripts
ENSMUST00000031032 ENSMUSP00000031032
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 39 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 39 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003824 catalytic activity
GO:0004721 phosphoprotein phosphatase activity
GO:0004722 protein serine/threonine phosphatase activity
GO:0005515 protein binding
GO:0046872 metal ion binding
Biological Process
GO:0006470 protein dephosphorylation
GO:0007050 cell cycle arrest
GO:0035970 peptidyl-threonine dephosphorylation
Cellular Component
GO:0005634 nucleus
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000115241
View Gene Order
ENSBTAG00000019522
Not yet available
Cross-References
SwissProt Q61074
TrEMBL
UniProt Splice Variant
Entrez Gene 14208
UniGene Mm.14501
RefSeq NM_008014
OMIM
CCDS CCDS19179
HPRD
IMGT
MGI ID MGI:106065
MGI Symbol Ppm1g
EMBL BC009004 U42383
GenPept AAC26322 AAH09004
RNA Seq Atlas 14208

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca