Version 5.4
| Mus musculus Protein: Ptpn20 | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Summary | |||||||||
| InnateDB Protein | IDBP-148548.6 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | Ptpn20 | ||||||||
| Protein Name | protein tyrosine phosphatase, non-receptor type 20 | ||||||||
| Synonyms | typ; | ||||||||
| Species | Mus musculus | ||||||||
| Ensembl Protein | ENSMUSP00000022508 | ||||||||
| InnateDB Gene | IDBG-148546 (Ptpn20) | ||||||||
| Protein Structure |
|
||||||||
| UniProt Annotation | |||||||||
| Function | Tyrosine-protein phosphatase targeted to sites of actin polymerization in response of varied extracellular stimuli. Has tyrosine phosphatase activity towards various tyrosyl phosphorylated substrates. | ||||||||
| Subcellular Localization | Nucleus {ECO:0000250}. Cytoplasm {ECO:0000250}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000250}. Note=Colocalizes with the microtubule-organizing center and intracellular membrane compartments. {ECO:0000250}. | ||||||||
| Disease Associations | |||||||||
| Tissue Specificity | Testis-specific. Specifically expressed in testicular germ cells that undergo meiosis (at protein level). {ECO:0000269PubMed:9407093}. | ||||||||
| Comments | |||||||||
| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
|
||||||||
| Gene Ontology | |||||||||
Molecular Function |
|
||||||||
| Biological Process |
|
||||||||
| Cellular Component |
|
||||||||
| Protein Structure and Domains | |||||||||
| PDB ID | MGI:1196295 | ||||||||
| InterPro |
IPR000242
Protein-tyrosine phosphatase, receptor/non-receptor type IPR000387 Protein-tyrosine/Dual specificity phosphatase IPR003595 Protein-tyrosine phosphatase, catalytic IPR029021 Protein-tyrosine phosphatase-like |
||||||||
| PFAM |
PF00102
|
||||||||
| PRINTS |
PR00700
|
||||||||
| PIRSF | |||||||||
| SMART |
SM00194
SM00404 |
||||||||
| TIGRFAMs | |||||||||
| Post-translational Modifications | |||||||||
| Modification | |||||||||
| Cross-References | |||||||||
| SwissProt | O55082 | ||||||||
| PhosphoSite | PhosphoSite-O55082 | ||||||||
| TrEMBL | |||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 19256 | ||||||||
| UniGene | Mm.8019 | ||||||||
| RefSeq | NP_033004 | ||||||||
| MGI ID | |||||||||
| MGI Symbol | Ptpn20 | ||||||||
| OMIM | |||||||||
| CCDS | CCDS36870 | ||||||||
| HPRD | |||||||||
| IMGT | |||||||||
| EMBL | AK029493 BC139817 D64141 | ||||||||
| GenPept | AAI39818 BAA23761 BAC26476 | ||||||||