Version 5.4
| Mus musculus Gene: Ptpn20 | |||||||||
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| Summary | |||||||||
| InnateDB Gene | IDBG-148546.6 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | Ptpn20 | ||||||||
| Gene Name | protein tyrosine phosphatase, non-receptor type 20 | ||||||||
| Synonyms | typ | ||||||||
| Species | Mus musculus | ||||||||
| Ensembl Gene | ENSMUSG00000021940 | ||||||||
| Encoded Proteins |
protein tyrosine phosphatase, non-receptor type 20
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| Protein Structure |
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| Useful resources | Stemformatics EHFPI ImmGen | ||||||||
| Entrez Gene | |||||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000204179:
The product of this gene belongs to the family of classical tyrosine-specific protein tyrosine phosphatases. Many protein tyrosine phosphatases have been shown to regulate fundamental cellular processes and several are mutated in human diseases. Chromosome 10q contains a segmental duplication resulting in multiple copies of the protein tyrosine phosphatase, non-receptor type 20 gene. The two nearly identical copies are designated as PTPN20A and PTPN20B. A third copy is only partially duplicated and contains a pseudogene, designated as PTPN20C. This gene encodes the more centromeric copy, PTPN20A. Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008] The product of this gene belongs to the family of classical tyrosine-specific protein tyrosine phosphatases. Many protein tyrosine phosphatases have been shown to regulate fundamental cellular processes and several are mutated in human diseases. Chromosome 10q contains a segmental duplication resulting in multiple copies of the protein tyrosine phosphatase, non-receptor type 20 gene. The two nearly identical copies are designated as PTPN20A and PTPN20B. A third copy is only partially duplicated and contains a pseudogene, designated as PTPN20C. This gene encodes the more telomeric copy, PTPN20B. Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008] The product of this gene belongs to the family of classical tyrosine-specific protein tyrosine phosphatases. Many protein tyrosine phosphatases have been shown to regulate fundamental cellular processes. The encoded protein appears to be targeted to sites of actin polymerization. A pseudogene of this gene has been defined on chromosome 10. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2014] |
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| Gene Information | |||||||||
| Type | Protein coding | ||||||||
| Genomic Location | Chromosome 14:33589270-33640754 | ||||||||
| Strand | Forward strand | ||||||||
| Band | B | ||||||||
| Transcripts |
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| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||
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Species
Homo sapiens
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Gene ID
Gene Order
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| Cross-References | |||||||||
| SwissProt | O55082 | ||||||||
| TrEMBL | |||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 19256 | ||||||||
| UniGene | Mm.8019 | ||||||||
| RefSeq | NM_008978 XM_006518730 | ||||||||
| OMIM | |||||||||
| CCDS | CCDS36870 | ||||||||
| HPRD | |||||||||
| IMGT | |||||||||
| MGI ID | MGI:1196295 | ||||||||
| MGI Symbol | Ptpn20 | ||||||||
| EMBL | AK029493 BC139817 D64141 | ||||||||
| GenPept | AAI39818 BAA23761 BAC26476 | ||||||||
| RNA Seq Atlas | 19256 | ||||||||