Version 5.4
Mus musculus Protein: Ahsg
Summary
InnateDB Protein IDBP-148708.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ahsg
Protein Name alpha-2-HS-glycoprotein
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000023583
InnateDB Gene IDBG-148706 (Ahsg)
Protein Structure
UniProt Annotation
Function Probably involved in differentiation.
Subcellular Localization Secreted.
Disease Associations
Tissue Specificity Liver is the major site of synthesis, but fetuin is also expressed in limb buds and other extrahepatic tissues during development.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 18 experimentally validated interaction(s) in this database.
They are also associated with 16 interaction(s) predicted by orthology.
Experimentally validated
Total 18 [view]
Protein-Protein 18 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 16 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004869 cysteine-type endopeptidase inhibitor activity
Biological Process
GO:0001503 ossification
GO:0006953 acute-phase response
GO:0010951 negative regulation of endopeptidase activity
GO:0030502 negative regulation of bone mineralization
GO:0045087 innate immune response (InnateDB)
GO:0050727 regulation of inflammatory response
GO:0050766 positive regulation of phagocytosis
Cellular Component
GO:0005615 extracellular space
GO:0070062 extracellular vesicular exosome
GO:0072562 blood microparticle
Protein Structure and Domains
PDB ID MGI:107189
InterPro IPR000010 Proteinase inhibitor I25, cystatin
PFAM PF00031
PRINTS
PIRSF
SMART SM00043
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P29699
PhosphoSite PhosphoSite-P29699
TrEMBL Q3UEK9
UniProt Splice Variant
Entrez Gene 11625
UniGene
RefSeq NP_038493
MGI ID
MGI Symbol Ahsg
OMIM
CCDS CCDS28071
HPRD
IMGT
EMBL AF007900 AJ002146 AK133523 AK149474 BC012678 BC019822 CH466521 S96534
GenPept AAB22070 AAB81718 AAH12678 AAH19822 BAE21704 BAE28902 CAA05210 EDK97636

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca