InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Dlc1

Summary

InnateDB Protein

IDBP-149177.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Dlc1

Protein Name

deleted in liver cancer 1

Synonyms

A730069N07Rik; Arhgap7; dlc-1; HP; STARD12;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000033923

InnateDB Gene

IDBG-149173 (Dlc1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.

Predicted by orthology
Total	6 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005100	Rho GTPase activator activity
GO:0005515	protein binding
GO:0008289	lipid binding
GO:0042169	SH2 domain binding

Biological Process

GO:0001843	neural tube closure
GO:0003007	heart morphogenesis
GO:0006915	apoptotic process
GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0007165	signal transduction
GO:0008285	negative regulation of cell proliferation
GO:0008360	regulation of cell shape
GO:0021575	hindbrain morphogenesis
GO:0030036	actin cytoskeleton organization
GO:0030336	negative regulation of cell migration
GO:0030900	forebrain development
GO:0032321	positive regulation of Rho GTPase activity
GO:0032956	regulation of actin cytoskeleton organization
GO:0035023	regulation of Rho protein signal transduction
GO:0035024	negative regulation of Rho protein signal transduction
GO:0035307	positive regulation of protein dephosphorylation
GO:0048041	focal adhesion assembly
GO:0051497	negative regulation of stress fiber assembly
GO:1900119	positive regulation of execution phase of apoptosis